Besides CHH, several cancer-genome studies have revealed RMRP SCNAs due to focal amplifications (Zack et al., 2013; Rheinbay et al., 2020), and the RMRP promoter was found to contain a breast-cancer associated mutation hotspot, impacting RMRP transcription (Rheinbay et al., 2017). This evidence concerns the gene RMRP and cancer.