Consequently, PVT1 was identified as a prognostic marker for cancer patient’s overall survival, and elevated PVT1 expression was found to associate with advanced tumor severity stage according to the tumor-node-metastasis (TNM) classification scheme (Lu et al., 2017; Martini et al., 2017; He et al., 2018; Boloix et al., 2019). Here, PVT1 is linked to cancer.