IFNAR1 and neoplasm: -IFNα decreased COX-2, TPL2, ERK, IKK α/β, & cAMP levels but little effect on JAK/STAT-TPL2 co-IP with IFNAR2 (not IFNAR1), IFNα & TPL2i decreased pTPL2-IFNAR2-IFNα + roflumilast synergistically suppressed tumor growth, cAMP & PGE2 sera levels in mice