CD68 and rheumatoid arthritis: We first performed semi-quantitative evaluations of conventional histological scores (synovial hyperplasia, inflammatory infiltrates, vascularity, fibrinoid necrosis) and CD3, CD20 and CD68 positive cells in paired synovial biopsies obtained from large (needle-arthroscopy) and small (US-guided biopsies) swollen joints from 10 patients with active RA.