ADORA2B: caffeine (phase I completed)VDR: calcipotriene (phase IV), calcitriol (phase II), becocalcidiol (phase II), pefcalcitol (phase II), ergocalciferol (psoriasis vulgaris-phase 0), cholecalciferol (phase 0). The gene discussed is VDR; the disease is psoriasis vulgaris.