A near-identical cluster to OTU1 was also found to be expanded and dominant in a majority of challenged repertoires at day 7 and 11 post-infection (Supplementary Figure 7B), and both clusters were also observed in analyses of publicly available RNA-seq data sets for P. chabaudi (AS) and P. chabaudi (CB) (accession E-ERAD-221 and E-ERAD-289 respectively, Supplementary Figure 7C), showing a similar temporal pattern of expansion. This evidence concerns the gene OTUB1 and infection.