Both integrations revealed a dense minimally-connected network containing many novel nodes (Figures 4B, C, highlighted in orange), including: EOMES (eomesodermin), which is involved in the differentiation of CD8+ T cells, active against viral infections (31); VCP involved in T cell activation (32); and EGR1 that stimulates T cell activation and promotes IL2 production (33). The gene discussed is VCP; the disease is viral infectious disease.