MME and retinal disorder: While scleral cartilage, rete mirabile vascular elements and retinal layers appear relatively undisturbed in vaccinated and V. anguillarum challenged animals (Figures 13A, C), non-vaccinated infected animals show non-artifactual loss of normal retinal layers, thickening and disorganization of retinal tissues (Figures 13B, D) and large numbers of CD10+ cells associated with these retinal lesions (Figures 13D, G), similar to those we described previously as various forms of retinopathy (61–63).