MS and MOGAD share many features including inflammatory demyelination in brain, oligodendrocyte death and infiltration by T and B lymphocytes and macrophages, and are distinguishable mainly by clinical, pathological and radiological criteria, and the presence of serum MOG IgG antibodies and predominance of brain-infiltrating CD4+ over CD8+ T cells in MOGAD (3, 4). Here, CD8A is linked to myeloid sarcoma.