Cytokine storm may cause dysfunction of NK and CD cells and may include other proinflammatory cytokines or chemokines such as IL-17, IL-21, IL-22, IL-6, TNF-α, chemokine ligand 10 and 2, IL-2R, IL-8, IL-10, which may also participate in ARDS/ALI and multi-organ failure (4). Here, IL21 is linked to acute respiratory distress syndrome.