Examples of this include, the bioactive lipid, lysophosphatidic acid, and its receptor, LPAR-1 in breast cancer (111), chemokines, CXCL8/IL8 and CXCR1 and CXCR2 in melanoma, pancreatic cancer and gastric tumors (112) and CXCL12 and CXCR4 in multiple cancers (113). This evidence concerns the gene LPAR1 and familial pancreatic carcinoma.