In BC, 25 (11.6%) proteins have altered expression; 12 proteins were under expressed MTR, RAC1, MED1, ERBB4, GAB1, GATA6, LPIN1, LPP, NAMPT, PGR, RPS26, TGFBR3, and 13 were over expressed GATA4, AOPEP, BMP6, CCL2, CDK2, EDN1, GPER1, MTHFR, NR1D1, PLIN1, PLTP, PON1, TNFRSF1B (Figure 5B) (Supplementary Table 18). This evidence concerns the gene PGR and breast cancer.