MOG and acute disseminated encephalomyelitis: A nationwide study (11) in the Netherlands indicates that the overall incidence of MOG-IgG-seropositive disorders is 0.16 per 100,000 people, with a higher seropositivity in children (0.31/100,000) than in adults (0.13/100,000), and the most common presenting phenotype is ADEM in children (56%) and ON in adults (44%).