The latter have been implicated in rheumatoid cachexia, with reports of reduced lean body mass (LBM) correlating with elevated serum levels of IL-6 and CRP (Munro and Capell, 1997; Engvall et al., 2008) In other chronic inflammatory conditions than RA, like Crohn’s disease, correlations with weight loss have also been described (Nakashima et al., 1998; Bossola et al., 2000; Mantovani et al., 2001; Dulger et al., 2004; Tas et al., 2005; Baker et al., 2016), indicating that the relation between systemic inflammation and cachexia may extend beyond the diseases described here. The gene discussed is CRP; the disease is Cachexia.