Zhang et al. (2016) confirmed that fenofibrate, a lipid-lowering drug, prevents fibrosis and inflammation in the hearts of subjects with type 1 diabetes upregulating autophagy mediated by sirtuin1. Wei et al. (2017) also reported that enhancing autophagy by inhibiting mTOR in type 1 diabetic rats restrained the development of diabetes-associated cardiomyopathy. This evidence concerns the gene MTOR and type 1 diabetes mellitus.