Similarly, when comparing PPMI and controls, co-carriage of both PGLYRP4 rs10888557 GC and TLR2 rs3804099 CC increased PD risk by ~1.8-fold but this was not significant in either naïve [OR = 1.835 (0.809–4.160), p = 0.146] or corrected models [OR = 1.846 (0.813–4.188), p = 0.143], likely due to the small number of individuals with both risk alleles in control (n = 10) or PD (n = 15). Here, TLR2 is linked to Parkinson disease.