BDNF and Parkinson disease: Recent studies using cell lines treated with the neurotoxin 1-methyl-4-phenylpyridinium (MMP+), which in vivo reproduces the same neurodegeneration pattern observed in PD patients, induced the upregulation of miRNA-210, which correlated with poor disease outcome and dopaminergic neuron damage by targeting BDNF (Zhang S. et al., 2018).