miRNA-23a is upregulated in GBM samples according to the TCGA database (Bhaskaran et al., 2019) and was recently identified as a key modulator of GBM invasion by targeting Homeobox 10 and increasing ras homolog family member (Rho)A, RhoC, and urokinase-type plasminogen activator receptor (uPAR) expression (Hu et al., 2013; Yachi et al., 2018). This evidence concerns the gene RHOC and glioblastoma.