SOD1 and amyotrophic lateral sclerosis: However, when spinal cord homogenates from paralyzed SOD1-G93A mice were injected into the spinal cord of SOD1-G85R:YFP mice at PN0 (postnatal day 0), some (~50%) of these mice subsequently developed ALS-like phenotypes, including paralysis as early as 6 months of age, as well as reduced life-span (Ayers et al., 2014).