TBC1D4 and diabetes mellitus: HO carriers of the TBC1D4 variant were in higher number in the diabetes group compared to the normoglycemia group, n = 47 (13.7%) and n = 71 (2.3%) and conversely TBC1D4 WT genotype was lower in the diabetes group than the normoglycemia group n = 205 (59.8%) and n = 2205 (70.3%) respectively.