ESR1 and osteoporosis: In total, 102 patients (23.0%) had been diagnosed as having osteoporosis and were treated with bisphosphonates (n = 56), selective estrogen receptor modulators (n = 36), daily or weekly preparations of teriparatide (n = 4), eldecalcitol (n = 3), denosumab (n = 2), or estradiol (n = 1).