In these experiments, mice were injected intravenously (i.v.)with histones, and 2 h later when multiple organ failure is clearly evident, they received mCBS or MTS intraperitoneally (i.p.)and 30 min later were sacrificed, plasma collected, and analyzed for ALT, LDH, creatinine, and Hb content (Fig. 5a). This evidence concerns the gene GSTM1 and Multiple Organ Failure.