The novel FUT2/MAMSTR signal was replicated in the COPSAC birth cohorts (COPSAC2000 and COPSAC2010 combined), where there was evidence of an association between rs281379 and asthma before the age of 6 years (OR = 1.38 (95% CI = 1.09–1.75), Preplication 1 = 0.008). Here, MAMSTR is linked to asthma.