Among the 97 proteins, 38 are targets of existing drugs, including 15 proteins (PLOD2, COMT, DCTPP1, GLA, ERO1LB, SDF2, MARK3, ERLEC1, FKBP7, PTGES2, EIF4E2, MFGE8, IL17RA, COL6A1, and PLAT) (eight with no known pQTL) that were previously identified3 as interacting with structural or non-structural proteins encoded in the SARS-CoV-2 genome and 16 proteins (CD14, F2, F5, F8, F9, F10, FGB, IL1R1, IL2RA, IL2RB, IL6R, IL6ST, PLG, SERPINC1, SERPINE1, and VWF) (seven with no known pQTL) that encode biomarkers related to COVID-19 severity7, prognosis, or outcome. The gene discussed is IL6ST; the disease is COVID-19.