AP2A2 and COVID-19: Among 86 considered proteins, we identified a highly connected subgroup of 24 proteins including 19 SARS-CoV-2-human protein interaction partners (e.g., RAB1A, RAB2A, AP2A2, PLD3, KDEL2, GDP/GTP exchange protein, PPT1, GT251, or PKP2) and five proteins related to cytokine storm (IL-1Rrp2 and IL-1Ra), fibrinolysis (PAI-1), coagulation (coagulation factor X(a)), and severity of COVID-19 (GSN (gelsolin)) (Fig. 3).