PDGFRB and liver dysplastic nodule: We found that miRNAs which were upregulated in kidney biopsies from patients with DN (mean estimated glomerular filtration rate [eGFR] 33 mL/min/1.73 m2) compared with controls (eGFR 101 mL/min/1.73 m2), corresponded to macrophage-enriched miRNAs (e.g., miR-16, miR-146b) and PDGFR-β+–enriched miRNAs (e.g., miR-199a-3p, miR-214-3p), with downregulated miRNAs mapping to PT cell–enriched miRNAs (Figure 7B and ref. 11).