Several studies reported the overexpression of several PKs in primary as well as in metastatic breast cancers such as vascular endothelial growth factor receptor (VEGFR)18–20, fibroblast growth factor receptor (FGFR)20–21, platelet-derived growth factor receptor (PDGFR)20,22, cyclin dependent kinases (CDKs) and their activating cyclins23–27, and glycogen synthase kinase 3β (GSK-3β)28–30 and references therein. The gene discussed is GSK3B; the disease is breast carcinoma.