This observation was unique to cutaneous melanoma as CD74 expression in uveal melanoma did not predict prognosis, rather represents trend for poor outcome (p = 0.16) Other inflammatory markers that involved in our protein panel, were also in agreement with our results that showing no statistical significance with MIF (p = 0.292), NOS2 (p = 0.405), PTGES (p = 0.102), PTGES2 (p = 0.292) (Figure 4 and Figure S1). The gene discussed is PTGES2; the disease is cutaneous melanoma.