SCT and leptospirosis: Our findings showing that the rGspDLC protein conferred up to 75% protection against disease in the hamster model, the fact that GspD is conserved, abundant [18], and a putative functionally important protein in pathogenic Leptospira species, suggest that the T2S GspD secretin of Leptospira might well be considered as a potential immunogen to be used for protection against leptospirosis.