CYP2C19 and coronary artery disorder: Cytochrome P450 2C19 (CYP2C19), as one of the main cytochromes P450s drug metabolic enzymes in human body, is encoded by chromosome 10 and expressed in the human liver.[22] It is the most polymorphic member of CYP2 C subfamily.[23]CYP2C19 gene mutation can change the activity of human related enzymes, affect the metabolic process of related drugs, and lead to cardiovascular events in patients with CHD.