Previous reports have suggested no significant difference between the prognosis of isolated MS and MS with concomitant AML.[5–7] According to a recent study, approximately 55% of MS cases also expressed CD7.[5] CD7-postive AML exhibited high blast cell counts and poor outcomes.[8–10] Additionally, it has been reported that leukemic pleural effusion could also be an initial manifestation of CD7-positive AML.[11]. The gene discussed is CD7; the disease is acute myeloid leukemia.