For example, adiponectin inhibited NF-κB and its transcription factors expression, protecting the aorta from atherosclerotic injury by reducing inflammation.[20] Adiponectin accumulated in the vasculature by T-cadherin, protecting neointima proliferation, and atherosclerosis.[21] Adiponectin prevented atherosclerosis by reducing oxidative stress.[22]. This evidence concerns the gene ADIPOQ and atherosclerosis.