CD68 and acute myeloid leukemia: It can precede or coincide with acute myeloid leukemia (AML).[4] Detection of myeloid sarcoma is equivalent to the diagnosis of AML.[5] The immunohistochemistry is used to confirm the diagnosis: the most common markers are MPO, CD117, and CD68.[6] Multiple mutations have been reported to be linked with myeloid sarcoma.