Previous reports have evidenced that EIF5A knockdown using small hairpin RNA in cervical cancer cells (Mémin et al., 2014), pancreatic ductal adenocarcinoma cells (Fujimura et al., 2015), and HeLa cells (Mandal et al., 2016) regulates proteins involved in migration, invasion, proliferation, endoplasmic reticulum (ER) stress, and/or unfolded protein response. The gene discussed is EIF5A; the disease is pancreatic ductal adenocarcinoma.