Consistent with the hypothesis, cellular analysis revealed that resistant Tac mice experience a significant increase in antigen-experienced CD4 T cells (Figures 1B and 1C), Tfh cells (Figures 1D and 1E), plasmablasts (Figures 1F and 1G), and GC B cells (Figures 1H and 1I) at later stages of the infection. This evidence concerns the gene CD4 and infection.