CHL1 and neoplasm: In order to establish whether CHL1 gene expression was related to cytogenetic markers of grim prognosis recurrently observed in NB (chromosome 1p deletion, 11q deletion, and 17q gain) [23], we analyzed microarray expression results from two independent datasets, Lastowska and Maris, that provide information about tumor 1p, 11q, and 17q status.