As shown in Fig 1E, 1F and 1G, SARS-CoV-2 infection of human primary monocytes up-regulated the pathways involved in lipid uptake such as CD36, the major transcriptional factors involved in lipogenesis, PPARγ and SREBP-1, and the enzyme DGAT-1, which is involved in triacylglycerol synthesis, after 24 hours of infection. This evidence concerns the gene SREBF1 and infection.