Regarding the levels of methylation of the LPL gene, no relationship was found in the present study between the methylation levels of this gene and LDL-C concentrations, corroborating studies based on the analysis of the visceral adipose tissue of individuals with metabolic syndrome [12], of leukocytes from individuals with familial hypercholesterolemia [57] and of the placenta of pregnant women with gestational diabetes mellitus [58], thus also in individuals with defined clinical diagnoses. This evidence concerns the gene LPL and familial hypercholesterolemia.