In the multivariate regression analysis, MDA was the only variable that positively correlated with LDL-C concentrations, calculated based on the Friedewald [36] and Martin et al. [13] equations, in all multivariate models analysed and composed of independent variables such as methylation levels of the LPL, ADRB3 and MTHFR genes, oxidative stress, inflammation, abdominal obesity, food intake and epidemiological variables. The gene discussed is MTHFR; the disease is Abdominal obesity.