ADAMTS13 and hemolytic-uremic syndrome: However, nephrological disorders have been described, as thrombotic microangiopathy (TMA) (Michailidou & Wilde, 2019; Walsh & Johnson, 2019), whose most frequent forms are thrombotic thrombocytopenic purpura (TTP) characterized by an insufficient ADAMTS13 activity and hemolytic uremic syndrome (HUS).