Considering the impact of EBV in the pathogenesis of PTLD and the role of cytotoxic T cells in antiviral response, not surprisingly, we found increased numbers of CD8-positive T cells (p = 0.01) and Granzyme B-positive cytotoxic effector cells (p = 0.0028), which can also include TAMs [2, 13], indicating a more cytotoxic environment [15, 42, 44]. Here, CD8A is linked to post-transplant lymphoproliferative disease.