In two large studies, no infective transmission between humans of AD and PD occurred in cadaver-derived human growth hormone (HGH) recipients [25] or blood transfusion recipients [4] and to date there are no reports of induced-ND following organ transplant, as would be expected in typical prion diseases, such as Creutzfeldt-Jakob disease [4, 50]. This evidence concerns the gene GH1 and Creutzfeldt Jacob disease.