PPARG and hepatocellular carcinoma: Hispidulin can activate PPARγ through the activation of adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) and extracellular regulated protein kinases (ERK) signaling pathways, thereby suppressing the oncogenesis and metastasis of hepatocellular carcinoma both in vitro and in vivo (11).