As shown in Figures 5B–F, high mRNA expression levels of CXCR3 (p = 0.023), CXCR4 (p = 0.00068), CXCR5 (p = 0.026), and CXCR6 (p = 0.036) were significantly related to worse OS of patients with ccRCC, while high mRNA expression of CXCR2 (p = 0.01) were obviously associated with better OS time. This evidence concerns the gene CXCR5 and nonpapillary renal cell carcinoma.