CD163 and colorectal carcinoma: CD163 is mainly identified to be the unique monocyte/macrophage biomarker for M2 macrophages, and is tightly related to the dismal prognosis and aggressive phenotype of CRC, LUAD, LUSC, and OSCC (Cao et al., 2019; Li et al., 2019; Yang C. et al., 2019; Yang G. et al., 2019).