The expression level of IGFL1 in the samples with high expression of IGFLR1 and low expression of IGFLR1 was compared and the influence of the expression level of IGFL1 in the samples with high expression of IGFLR1 on the prognosis of ccRCC patients was analyzed by “survival” R package. This evidence concerns the gene IGFL1 and nonpapillary renal cell carcinoma.