Quercetin reverses the apoptosis resistance in IPF fibroblasts by promoting the transcription of FasL receptor and Cav-1 gene (Hohmann et al., 2019), while the combination of dasatinib and quercetin (D+Q) selectively kills senescent fibroblasts to ameliorate the progression of pulmonary fibrosis in mice (Schafer et al., 2017). Here, CAV1 is linked to idiopathic pulmonary fibrosis.