PVT1 and colorectal carcinoma: Interestingly, some of the identified lncRNAs were upregulated in the CRC-treated T cells as compared to the non-CRC groups such as MIAT, MEG3, and LINC00426. Whereas certain lncRNAs were downregulated, such as PVT1 and LINC00520. Nevertheless, careful interpretation of this data is needed as the T cells used were different between the CRC and non-CRC EVs and this could contribute to the high differences.