For IL-17A, elevated expression of this cytokine was observed in the T cells incubated with Non-CRC EVs, significance (p < 0.05) was observed between the HighBMI-non-CRC and HighBMI-CRC (p = 0.023), as well as for the overall Non-CRC against CRC (p = 0.007). The gene discussed is IL17A; the disease is colorectal carcinoma.