Infection/Inflammation/AllergicHigher expression on lymphocytes in hypersensitivity pneumonitis (123)*CancerTissue expression higher in breast cancer cells versus healthy breast tissue (131)Monogenic DisordersADAM17/TACE deficiency a/w reduced LPS-stimulated TNFa and sTNFR2 in PBMC (132, 133),. The gene discussed is TNF; the disease is infection.