Table 2 lists the top 10 most statistically significant DEGS in NASH, ordered by the magnitude of altered expression. The 10 DEGs included two up-regulated genes (CYP7A1, and PEG10), and eight down-regulated genes (FOSB, FOS, IL6, GADD45G, MYC, SLITRK3, JUNB, IGFBP2). Box plots of mRNA expression levels of the 10 DEGs are shown in Figure 2B. This evidence concerns the gene PEG10 and metabolic dysfunction-associated steatohepatitis.