As shown in Table 1, plasma levels of IL-6, IL-10, TNF-α, and SIRT1 varied significantly across MetS patients, non-MetS patients, and control subjects (F = 37.205, P < 0.001; F = 24.114, P < 0.001; F = 39.744, P < 0.001; F = 11.058, P < 0.001, respectively). The gene discussed is TNF; the disease is metabolic syndrome.