The concentrations of ANG-1, PDGF-BB, TIMP-2, and VEGFR2 (351.85 ng/mL, 34.95 pg/mL, 114.60 ng/mL, and 14.06 ng/mL, respectively) were significantly higher in NPDR samples than those in T2DM patients (286.81 ng/mL, 28.07 pg/mL, 105.01 ng/mL, and 11.91 ng/mL, respectively). The gene discussed is KDR; the disease is type 2 diabetes mellitus.