AKT1 and hepatocellular carcinoma: For the research on pathways related to FUT8 and tumor survival, many references indicate that FUT8 activates several related signaling pathways, including Ras/MAPKK signaling, c-Met signaling, Akt/mTOR signaling and Wnt/β-catenin signaling, which ultimately lead to hepatocellular carcinoma or colorectal cancer affects the overall survival of patients [31–33].