Consistently, enhanced EPB41L3 expression was also observed in osteosarcoma tissues (versus OBs in GSE14359, fold change=2.5845, p=0.0032; versus OBs in GSE12865, fold change=3.6075, p=0.0001) and osteosarcoma lung metastasis tissues (versus OBs in GSE14359, fold change=2.0996, p=0.0172) (Figure 1A). The gene discussed is EPB41L3; the disease is osteosarcoma.